Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name pav
Flybase description The gene pavarotti is referred to in FlyBase by the symbol Dmel\pav (CG1258, FBgn0011692).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -44.4443 -23.7134 -23.85138 -36.2256 -34.958687 -28.6887 -52.14168 -31.17683
    Affimetrix absolute value 2.95 3.086 3.608 3.242 3.634 3.731 2.851 3.329
    Affymetric present call in "x" number of chips 0 0 0 0 0 1 0 1
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: microtubule motor activity.
There is experimental evidence that it is involved in the biological process: female meiosis chromosome segregation; smoothened signaling pathway; contractile ring contraction involved in cell cycle cytokinesis; regulation of Wnt receptor signaling pathway; maintenance of protein location in cell; cell fate determination; positive regulation of NFAT protein import into nucleus; mitotic spindle organization; cytokinesis; neurogenesis.
44 alleles are reported.
The phenotypes of these alleles are annotated with 17 unique terms, many of which group under: organ system; female germline cyst; multicellular structure; organ system subdivision; organelle; presumptive embryonic/larval nervous system; cytoplasmic part; non-connected developing system; multi-cell-component structure; anatomical structure.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Kinesin, motor domain; Kinesin, motor region, conserved site.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed within 00-12 hour embryonic stages.
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