Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Tig
Flybase description The gene Tiggrin is referred to in FlyBase by the symbol Dmel\Tig (CG11527, FBgn0011722).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -10.4944 -7.2002 -11.354652 -13.1116 -18.825834 -15.2699 -8.54979 -10.398906
    Affimetrix absolute value 5.017 4.784 4.732 4.682 4.556 4.638 5.514 4.907
    Affymetric present call in "x" number of chips 1 2 0 0 0 0 1 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: binding.
There is experimental evidence that it is involved in the biological process: axon guidance; cell-substrate adhesion; regulation of cell adhesion mediated by integrin; phagocytosis, engulfment.
9 alleles are reported.
The phenotypes of these alleles are annotated with 30 unique terms, many of which group under: hypodermal muscle of larval abdomen; organ system; larval abdominal segment 5; A1-7 oblique muscle; hypodermal muscle of larval abdominal 2; A1-7 ventral longitudinal muscle 3; abdominal 7 longitudinal muscle; abdominal segment 7; abdominal 6 longitudinal muscle; multi-cell-component structure; abdominal 3 ventral longitudinal muscle 4; adult segment.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Haem oxygenase-like, multi-helical.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression.
Peak expression observed within 12-24 hour embryonic stages, during early larval stages.
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