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Gene name | wee | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene wee is referred to in FlyBase by the symbol Dmel\wee (CG4488, FBgn0011737). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein tyrosine kinase activity. There is experimental evidence that it is involved in the biological process: mitotic cell cycle, embryonic; centrosome localization; centrosome separation; negative regulation of cyclin-dependent protein kinase activity; mitotic cell cycle checkpoint; nuclear division; spindle assembly; cell cycle. 15 alleles are reported. The phenotypes of these alleles are annotated with: wing margin; interommatidial bristle; mitotic cell cycle; adult thorax; wing; ommatidium; scutellum. It has one annotated transcript and one annotated polypeptide. Protein features are: Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase-like domain; Wee1-like protein kinase. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages. . |