Flygut: an atlas of the Drosophila adult midgut

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Gene name Fdh
Flybase description The gene Formaldehyde dehydrogenase is referred to in FlyBase by the symbol Dmel\Fdh (CG6598, FBgn0011768).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 2.7521 3.2342 2.777293 2.2419 2.057172 2.4856 3.24383 2.448495
    Affimetrix absolute value 9.867 9.31 9.642 9.55 9.796 9.871 10.231 9.504
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: S-nitrosoglutathione reductase activity; S-(hydroxymethyl)glutathione dehydrogenase activity; alcohol dehydrogenase (NAD) activity; octanol dehydrogenase activity.
There is experimental evidence that it is involved in the biological process: regulation of peptidyl-cysteine S-nitrosylation; visual learning.
16 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Alcohol dehydrogenase GroES-like; Alcohol dehydrogenase class III/S-(hydroxymethyl)glutathione dehydrogenase; Alcohol dehydrogenase superfamily, zinc-type; Alcohol dehydrogenase, C-terminal; Alcohol dehydrogenase, zinc-type, conserved site; GroES-like; NAD(P)-binding domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in adult female stages.
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