Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Hem
Flybase description The gene HEM-protein is referred to in FlyBase by the symbol Dmel\Hem (CG5837, FBgn0011771).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -4.2521 -1.2777 -3.327387 -1.5581 -4.784062 -2.0709 -2.60226 -4.611688
    Affimetrix absolute value 6.324 7.268 6.572 7.771 6.601 7.516 7.188 6.21
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence for 11 unique biological process terms, many of which group under: cellular component organization or biogenesis; anatomical structure development; cellular component organization or biogenesis at cellular level; organelle organization; actin filament-based process; cell projection organization; muscle cell differentiation; biological regulation; muscle organ development; organ development; localization; regulation of developmental process; sensory organ development; central nervous system development.
22 alleles are reported.
The phenotypes of these alleles are annotated with 23 unique terms, many of which group under: organ system subdivision; nervous system; multi-cell-component structure; presumptive embryonic/larval nervous system; peripheral nervous system; sensillum; commissure; organelle; organ system; sense organ; non-connected developing system.
It has one annotated transcript and one annotated polypeptide.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult female stages.
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