Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name BRWD3
Flybase description The gene BRWD3 is referred to in FlyBase by the symbol Dmel\BRWD3 (CG31132, FBgn0011785).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -6.4955 -2.7626 -5.026814 -4.111 -7.704393 -4.9851 -4.74513 -7.287976
    Affimetrix absolute value 5.723 6.154 5.897 6.366 5.844 6.263 6.329 5.496
    Affymetric present call in "x" number of chips 2 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Its molecular function is unknown.
There is experimental evidence that it is involved in the biological process: mitotic cell cycle G2/M transition DNA damage checkpoint; phagocytosis, engulfment.
17 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Bromodomain; Bromodomain, conserved site; Quinonprotein alcohol dehydrogenase-like; WD40 repeat; WD40 repeat 2; WD40 repeat, conserved site; WD40 repeat, subgroup; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-12 hour embryonic stages.
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