Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name nuf
Flybase description The gene nuclear fallout is referred to in FlyBase by the symbol Dmel\nuf (CG33991, FBgn0013718).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 2.1033 1.9918 -3.817995 -1.2613 -4.197338 -1.8334 1.97418 -2.114799
    Affimetrix absolute value 9.478 8.59 6.277 8.066 6.733 7.696 9.5 7.244
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: microtubule binding.
There is experimental evidence that it is involved in the biological process: sensory organ precursor cell fate determination; wing disc dorsal/ventral pattern formation; actin cytoskeleton reorganization.
38 alleles are reported.
The phenotypes of these alleles are annotated with: trichogen cell; macrochaeta; intersegmental nerve; scutellar bristle.
It has 12 annotated transcripts and 12 annotated polypeptides.
Protein features are: Rab-binding domain FIP-RBD.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.
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