Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name pck
Flybase description The gene pickel is referred to in FlyBase by the symbol Dmel\pck (CG14779, FBgn0013720).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 3.0491 1.1903 -5.301361 -2.7075 -6.737163 -2.9856 2.27055 -2.903616
    Affimetrix absolute value 10.016 7.861 5.797 6.96 6.019 6.988 9.709 6.781
    Affymetric present call in "x" number of chips 3 3 2 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Its molecular function is unknown.
There is experimental evidence that it is involved in the biological process: regulation of tube size, open tracheal system; establishment of glial blood-brain barrier; open tracheal system development; septate junction assembly.
7 alleles are reported.
The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: organ system; abdominal ventral denticle belt; embryonic/larval tracheal system; larval abdominal segment; portion of tissue; tracheal system; late extended germ band embryo; cuticle; primordium; dorsal trunk primordium; abdominal 5 ventral denticle belt.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Beta tubulin, autoregulation binding site.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression.
Peak expression observed within 06-12 hour embryonic stages.
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