Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name shot
Flybase description The gene short stop is referred to in FlyBase by the symbol Dmel\shot (CG18076, FBgn0013733).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 1.1773 3.4255 2.348566 2.1632 0.38711 2.0048 2.55962 0.809737
    Affimetrix absolute value 8.64 9.38 9.395 9.474 8.829 9.563 9.85 8.755
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence that it is involved in the biological process: negative regulation of microtubule depolymerization; dendrite morphogenesis; oocyte fate determination; regulation of axon extension; microtubule cytoskeleton organization; mushroom body development; open tracheal system development; branch fusion, open tracheal system; lumen formation, open tracheal system; axon midline choice point recognition.
79 alleles are reported.
The phenotypes of these alleles are annotated with 25 unique terms, many of which group under: organ system subdivision; organ system; late extended germ band embryo; multi-cell-component structure; primordium; ectoderm derivative; embryonic/larval neuron; integumentary specialisation; portion of tissue; presumptive embryonic/larval nervous system.
It has 22 annotated transcripts and 22 annotated polypeptides.
Protein features are: Actinin-type, actin-binding, conserved site; Calcium-binding EF-hand; Calponin homology domain; EF-HAND 2; EF-Hand 1, calcium-binding site; EF-hand-like domain; Growth-arrest-specific protein 2 domain; Plectin repeat; Spectrin repeat; Spectrin/alpha-actinin; Src homology-3 domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 18-24 hour embryonic stages.
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