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Gene name | alien | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene alien is referred to in FlyBase by the symbol Dmel\alien (CG9556, FBgn0013746). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding; nuclear hormone receptor binding; ligand-dependent nuclear receptor binding; protein homodimerization activity; transcription corepressor activity. There is experimental evidence that it is involved in the biological process: protein stabilization; mitotic cell cycle G2/M transition DNA damage checkpoint; negative regulation of transcription, DNA-dependent; neurogenesis; phagocytosis, engulfment. 3 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; mesothoracic tergum. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: PCI/PINT associated module; Proteasome component (PCI) domain; Tetratricopeptide-like helical; Winged helix-turn-helix transcription repressor DNA-binding. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, during late larval stages, during early pupal stages, in adult female stages. . |