Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name Bro
Flybase description The gene Brother is referred to in FlyBase by the symbol Dmel\Bro (CG7960, FBgn0013755).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -48.2108 -30.9313 -44.840364 -55.7096 -57.56236 -63.5575 -52.24971 -46.212249
    Affimetrix absolute value 2.82 2.682 2.714 2.596 2.923 2.572 2.862 2.735
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: transcription coactivator activity.
Based on sequence similarity, it is predicted to be involved in the biological process: positive regulation of transcription from RNA polymerase II promoter.
9 alleles are reported.
The phenotype of these alleles is annotated with: embryonic/first instar larval cuticle.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Core binding factor, beta subunit.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of no expression detected.
Peak expression observed within 00-06 hour embryonic stages.
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