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Gene name | Cp1 | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Cysteine proteinase-1 is referred to in FlyBase by the symbol Dmel\Cp1 (CG6692, FBgn0013770). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: cysteine-type endopeptidase activity. There is experimental evidence that it is involved in the biological process: autophagic cell death; salivary gland cell autophagic cell death. 34 alleles are reported. The phenotypes of these alleles are annotated with: egg; adult abdominal segment 3; adult abdominal segment 1; adult abdominal segment 5; wing; adult abdominal segment 2; adult abdominal segment 4. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Peptidase C1A, papain; Peptidase C1A, papain C-terminal; Peptidase, cysteine peptidase active site; Proteinase inhibitor I29, cathepsin propeptide. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes. . |