Flygut: an atlas of the Drosophila adult midgut

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Gene name Cyp6a8
Flybase description The gene Cytochrome P450-6a8 is referred to in FlyBase by the symbol Dmel\Cyp6a8 (CG10248, FBgn0013772).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -9.3396 -5.7429 -9.768902 -23.7633 -29.059359 -18.6573 -21.26538 -13.137593
    Affimetrix absolute value 5.28 5.189 5.039 3.824 3.924 4.377 4.19 4.606
    Affymetric present call in "x" number of chips 3 3 2 0 1 3 1 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: alkane 1-monooxygenase activity.
There is experimental evidence that it is involved in the biological process: response to caffeine; insecticide metabolic process; lauric acid metabolic process.
5 alleles are reported.
No phenotypic data is available.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Cytochrome P450; Cytochrome P450, E-class, group I; Cytochrome P450, E-class, group II; Cytochrome P450, conserved site.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression.
Peak expression observed within 18-24 hour embryonic stages, during early larval stages.
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