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| Gene name | imd | ||||||||||||||||||||||||||||||||||||
| Flybase description | The gene immune deficiency is referred to in FlyBase by the symbol Dmel\imd (CG5576, FBgn0013983). | ||||||||||||||||||||||||||||||||||||
| Expression data along the gut |
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| Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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| Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: death domain binding; protein binding. There is experimental evidence that it is involved in the biological process: immune response; response to bacterium; humoral immune response; positive regulation of innate immune response; nervous system development; positive regulation of antibacterial peptide biosynthetic process; antimicrobial humoral response; peptidoglycan recognition protein signaling pathway; antibacterial humoral response. 29 alleles are reported. The phenotype of these alleles is annotated with: embryonic/larval fat body. It has one annotated transcript and one annotated polypeptide. Protein features are: DEATH-like; Death. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 06-12 hour embryonic stages, during late larval stages, during early pupal stages. . |
