Flygut: an atlas of the Drosophila adult midgut

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Gene name Nrx-IV
Flybase description The gene Neurexin IV is referred to in FlyBase by the symbol Dmel\Nrx-IV (CG6827, FBgn0013997).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.4333 -2.2012 -7.74304 -4.873 -13.116373 -5.379 -0.4607 -7.486367
    Affimetrix absolute value 7.146 6.502 5.272 6.108 5.141 6.136 8.393 5.512
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: transmembrane receptor activity.
There is experimental evidence that it is involved in the biological process: dorsal closure; nerve maturation; regulation of tube size, open tracheal system; establishment of glial blood-brain barrier; septate junction assembly; axon ensheathment.
33 alleles are reported.
The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: organ system subdivision; organ system; adult segment; non-connected developing system; thoracic segment; dorsal trunk primordium; scolopidium; synapse; external compound sense organ; plasma membrane part.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Coagulation factor 5/8 type, C-terminal; Concanavalin A-like lectin/glucanase; Concanavalin A-like lectin/glucanase, subgroup; Epidermal growth factor-like; Epidermal growth factor-like, type 3; Galactose-binding domain-like; Laminin G domain; Laminin G, subdomain 2; Neurexin/syndecan/glycophorin C.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 06-18 hour embryonic stages, at stages throughout the pupal period.
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