Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Pk92B
Flybase description The gene Protein kinase at 92B is referred to in FlyBase by the symbol Dmel\Pk92B (CG4720, FBgn0014006).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -1.8141 -1.4444 -1.928714 -2.8134 -4.328302 -2.981 -2.04848 -2.982728
    Affimetrix absolute value 7.559 7.094 7.233 6.918 6.659 6.992 7.527 6.687
    Affymetric present call in "x" number of chips 3 3 2 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: MAP/ERK kinase kinase activity.
There is experimental evidence that it is involved in the biological process: regulation of cell shape; positive regulation of stress-activated MAPK cascade.
11 alleles are reported.
No phenotypic data is available.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain; Sterile alpha motif homology; Tetratricopeptide-like helical.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 00-18 hour embryonic stages, during early pupal stages, in adult female stages.
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