Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Rac2
Flybase description The gene Rac2 is referred to in FlyBase by the symbol Dmel\Rac2 (CG8556, FBgn0014011).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 0.814 2.3346 1.53699 3.4306 0.34345 2.3053 1.31893 0.840356
    Affimetrix absolute value 8.929 8.84 8.767 10.116 8.77 9.754 8.941 8.76
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: GTPase activity.
There is experimental evidence for 23 unique biological process terms, many of which group under: cellular component organization or biogenesis; localization; biological regulation; open tracheal system development; membrane organization; organelle organization; gland morphogenesis; response to stress; defense response to bacterium; embryonic development via the syncytial blastoderm; cell fate commitment.
19 alleles are reported.
The phenotypes of these alleles are annotated with 17 unique terms, many of which group under: organ system; multicellular structure; organ system subdivision; embryonic/larval hemocoel; external compound sense organ; adult segment; anatomical structure; sense organ; peripheral nervous system; embryonic pericardial cell; non-connected developing system.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Small GTP-binding protein domain; Small GTPase superfamily; Small GTPase superfamily, Rho type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-12 and 18-24 hour embryonic stages, during early pupal stages.
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