Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name bnl
Flybase description The gene branchless is referred to in FlyBase by the symbol Dmel\bnl (CG4608, FBgn0014135).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -29.5702 -13.985 -10.664921 -5.7865 -21.899525 -11.4838 -2.58871 -14.008909
    Affimetrix absolute value 3.523 3.834 4.779 5.91 4.445 5.081 7.237 4.52
    Affymetric present call in "x" number of chips 0 3 3 3 2 3 3 2
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: fibroblast growth factor receptor binding.
There is experimental evidence that it is involved in the biological process: filopodium assembly; cytoneme assembly; positive chemotaxis; genital disc development; open tracheal system development.
23 alleles are reported.
The phenotypes of these alleles are annotated with 14 unique terms, many of which group under: organ system; tracheal system; portion of tissue; multicellular structure; anatomical structure; non-connected developing system; adult trachea; late extended germ band embryo; presumptive embryonic/larval tracheal system; tracheal branch primordium.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Cytokine, IL-1-like; Heparin-binding growth factor/Fibroblast growth factor; Interleukin 1/heparin-binding growth factor.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression.
Peak expression observed within 00-18 hour embryonic stages, during late pupal stages.
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