Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name RhoL
Flybase description The gene rho-like is referred to in FlyBase by the symbol Dmel\RhoL (CG9366, FBgn0014380).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 2.4573 6.9846 6.180104 4.3285 4.504412 6.0576 0.50245 5.071179
    Affimetrix absolute value 9.704 10.411 10.782 10.496 10.917 11.16 8.767 10.529
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: GTPase activity.
There is experimental evidence that it is involved in the biological process: regulation of cell shape; border follicle cell migration; response to DNA damage stimulus; cell adhesion; mesoderm development.
17 alleles are reported.
The phenotypes of these alleles are annotated with: polar follicle cell; intersegmental nerve; follicle cell; border follicle cell; nurse cell.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Small GTP-binding protein domain; Small GTPase superfamily; Small GTPase superfamily, Rho type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression.
Peak expression observed within 12-24 hour embryonic stages, during late larval stages, during early pupal stages.
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