Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name betaggt-I
Flybase description The gene β subunit of type I geranylgeranyl transferase is referred to in FlyBase by the symbol Dmel\βggt-I (CG3469, FBgn0015000).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.4079 7.8141 1.406675 0.4743 -1.218207 -1.1138 -3.52092 1.446259
    Affimetrix absolute value 7.144 10.522 8.665 8.567 8.475 8.413 6.747 8.736
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: protein geranylgeranyltransferase activity.
There is experimental evidence that it is involved in the biological process: embryonic heart tube development; neurogenesis.
9 alleles are reported.
The phenotypes of these alleles are annotated with: cardioblast; embryonic pericardial cell.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Prenyltransferase/squalene oxidase; Terpenoid cylases/protein prenyltransferase alpha-alpha toroid.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 00-12 and 18-24 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in adult female stages.
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