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Gene name | eIF-4E | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Eukaryotic initiation factor 4E is referred to in FlyBase by the symbol Dmel\eIF-4E (CG4035, FBgn0015218). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: translation initiation factor activity; protein binding; eukaryotic initiation factor 4G binding; RNA cap binding; RNA 7-methylguanosine cap binding. There is experimental evidence for 14 unique biological process terms, many of which group under: cellular component organization or biogenesis; cell cycle; cell cycle process; gene expression; programmed cell death; organelle organization; primary metabolic process; cellular macromolecule biosynthetic process; cellular biosynthetic process; gland morphogenesis; biological regulation; cell death. 40 alleles are reported. The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: organ system; organ system subdivision; peripheral nervous system; external compound sense organ; thoracic segment; multicellular structure; cell cycle; synapse; epithelial furrow; adult segment. It has 7 annotated transcripts and 7 annotated polypeptides. Protein features are: Eukaryotic translation initiation factor 4E (eIF-4E), conserved site; Translation Initiation factor eIF- 4e; Translation Initiation factor eIF- 4e-like domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression. Peak expression observed within 00-06 and 12-18 hour embryonic stages, at stages throughout the pupal period, in adult female stages. . |