Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Hsp60
Flybase description The gene Heat shock protein 60 is referred to in FlyBase by the symbol Dmel\Hsp60 (CG12101, FBgn0015245).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 0.5267 2.0225 2.45279 1.8267 2.056429 1.5719 1.36026 2.138813
    Affimetrix absolute value 8.645 8.614 9.469 9.255 9.781 9.168 8.979 9.335
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: unfolded protein binding.
There is experimental evidence that it is involved in the biological process: cellular response to heat; mitochondrion organization.
56 alleles are reported.
The phenotypes of these alleles are annotated with: blastoderm embryo; tergite.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Chaperonin Cpn60; Chaperonin Cpn60, conserved site; Chaperonin Cpn60/TCP-1.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed at stages throughout embryogenesis, during early larval stages, during late pupal stages, in stages of adults of both sexes.
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