Flygut: an atlas of the Drosophila adult midgut

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Gene name Pi3K68D
Flybase description The gene Phosphotidylinositol 3 kinase 68D is referred to in FlyBase by the symbol Dmel\Pi3K68D (CG11621, FBgn0015278).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -6.3595 -2.8401 -1.877415 -1.2387 -2.774329 -0.4298 -6.17074 -2.161557
    Affimetrix absolute value 5.756 6.113 7.28 8.086 7.308 8.437 5.975 7.178
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: phospholipid binding; phosphatidylinositol-4-phosphate 3-kinase activity; 1-phosphatidylinositol-3-kinase activity.
There is experimental evidence that it is involved in the biological process: phosphatidylinositol phosphorylation; response to DNA damage stimulus; phagocytosis, engulfment.
12 alleles are reported.
The phenotype of these alleles is annotated with: embryonic/larval hemocyte.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Armadillo-type fold; C2 calcium-dependent membrane targeting; C2 calcium/lipid-binding domain, CaLB; C2 membrane targeting protein; Phosphatidylinositol 3-/4-kinase, catalytic; Phosphatidylinositol 3/4-kinase, conserved site; Phosphatidylinositol Kinase; Phosphoinositide 3-kinase, C2; Phosphoinositide 3-kinase, accessory (PIK) domain; Phosphoinositide 3-kinase, ras-binding; Phox homologous domain; Protein kinase-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages, in adult female stages.
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