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| Gene name | Pi3K92E | ||||||||||||||||||||||||||||||||||||
| Flybase description | The gene Pi3K92E is referred to in FlyBase by the symbol Dmel\Pi3K92E (CG4141, FBgn0015279). | ||||||||||||||||||||||||||||||||||||
| Expression data along the gut |
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| Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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| Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: phosphatidylinositol-4-phosphate 3-kinase activity; lipid kinase activity; 1-phosphatidylinositol-3-kinase activity; phosphatidylinositol-4,5-bisphosphate 3-kinase activity. There is experimental evidence for 22 unique biological process terms, many of which group under: biological regulation; cellular component organization or biogenesis; instar larval development; regulation of developmental process; response to stimulus; entry into diapause; phospholipid metabolic process; larval feeding behavior; gland morphogenesis; response to stress; embryonic development via the syncytial blastoderm; catabolic process; metamorphosis; multicellular organism reproduction. 31 alleles are reported. The phenotypes of these alleles are annotated with 29 unique terms, many of which group under: organ system; organ system subdivision; adult segment; external compound sense organ; cell part; thoracic segment; cytoplasmic part; imaginal precursor; multicellular structure; organelle; acellular anatomical structure. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Armadillo-type fold; C2 calcium/lipid-binding domain, CaLB; Phosphatidylinositol 3-/4-kinase, catalytic; Phosphatidylinositol 3-kinase, p85-binding; Phosphatidylinositol 3/4-kinase, conserved site; Phosphatidylinositol Kinase; Phosphoinositide 3-kinase, C2; Phosphoinositide 3-kinase, accessory (PIK) domain; Phosphoinositide 3-kinase, ras-binding; Protein kinase-like domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, during late larval stages, during early pupal stages, in adult female stages. . |
