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Gene name | Rala | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Ras-related protein is referred to in FlyBase by the symbol Dmel\Rala (CG2849, FBgn0015286). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: PDZ domain binding; GTPase activity. There is experimental evidence that it is involved in the biological process: innate immune response; regulation of cell morphogenesis; border follicle cell migration; R3/R4 cell fate commitment; regulation of Notch signaling pathway; negative regulation of JNK cascade. 33 alleles are reported. The phenotypes of these alleles are annotated with 16 unique terms, many of which group under: organ system subdivision; organ system; adult segment; external compound sense organ; thoracic segment; peripheral nervous system; humeral trabecule; imaginal precursor; portion of tissue; dorsal closure embryo; epithelial cell. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Small GTP-binding protein domain; Small GTPase superfamily; Small GTPase superfamily, Ral-like; Small GTPase superfamily, Ras type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in adult female stages. . |