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Gene name | kek1 | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene kekkon-1 is referred to in FlyBase by the symbol Dmel\kek1 (CG12283, FBgn0015399). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: epidermal growth factor binding. There is experimental evidence that it is involved in the biological process: negative regulation of epidermal growth factor receptor signaling pathway; cytokinesis; oogenesis; neurogenesis. 42 alleles are reported. The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: organ system; organ system subdivision; adult segment; thoracic segment; external compound sense organ; adult; cell part; cell periphery; egg; epithelial cell; cell; peripheral nervous system. It has one annotated transcript and one annotated polypeptide. Protein features are: Cysteine-rich flanking region, C-terminal domain; Immunoglobulin I-set; Immunoglobulin subtype 2; Immunoglobulin-like; Immunoglobulin-like fold; Leucine-rich repeat; Leucine-rich repeat, typical subtype. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed during early pupal stages. . |