Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name otp
Flybase description The gene orthopedia is referred to in FlyBase by the symbol Dmel\otp (CG10036, FBgn0015524).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -36.8842 -21.3072 -29.606769 -28.5649 -43.503178 -40.0926 -7.63822 -31.472417
    Affimetrix absolute value 3.219 3.214 3.305 3.579 3.348 3.238 5.642 3.334
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 3 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: DNA binding.
There is experimental evidence that it is involved in the biological process: lateral inhibition.
2 alleles are reported.
The phenotype of these alleles is annotated with: mesothoracic tergum.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Helix-turn-helix motif, lambda-like repressor; Homeobox; Homeobox, conserved site; Homeodomain-like; Homeodomain-related.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.
Peak expression observed within 06-24 hour embryonic stages, at stages throughout the larval period.
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