Flygut: an atlas of the Drosophila adult midgut

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Gene name Cpr
Flybase description The gene Cytochrome P450 reductase is referred to in FlyBase by the symbol Dmel\Cpr (CG11567, FBgn0015623).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 4.0512 5.6035 3.876313 2.7571 1.911702 2.6467 2.13354 2.769444
    Affimetrix absolute value 10.386 10.104 10.115 9.844 9.684 9.951 9.634 9.685
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: NADPH-hemoprotein reductase activity.
An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: oxidation-reduction process.
13 alleles are reported.
No phenotypic data is available.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: FAD-binding, type 1; Ferredoxin reductase-type FAD-binding domain; Flavodoxin; Flavodoxin/nitric oxide synthase; Flavoprotein pyridine nucleotide cytochrome reductase; NADPH-cytochrome P450 reductase; NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain-3; Oxidoreductase FAD/NAD(P)-binding; Riboflavin synthase-like beta-barrel.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed within 00-06 and 18-24 hour embryonic stages, during late pupal stages, in stages of adults of both sexes.
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