Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name NetB
Flybase description The gene Netrin-B is referred to in FlyBase by the symbol Dmel\NetB (CG10521, FBgn0015774).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -30.2916 -23.5089 -25.753863 -11.382 -29.398063 -13.9728 -30.99155 -25.302114
    Affimetrix absolute value 3.488 3.072 3.508 4.893 3.887 4.783 3.625 3.643
    Affymetric present call in "x" number of chips 0 0 0 3 2 3 3 1
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Its molecular function is unknown.
There is experimental evidence that it is involved in the biological process: motor axon guidance; salivary gland boundary specification; axon guidance; dendrite guidance.
30 alleles are reported.
The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: organ system subdivision; organ system; peripheral nervous system; adult segment; non-connected developing system; multicellular structure; cell part; embryonic foregut; axon; larval abdominal segment.
It has 6 annotated transcripts and 6 annotated polypeptides.
Protein features are: EGF-like, laminin; Laminin, N-terminal; Netrin domain; Netrin module, non-TIMP type; Tissue inhibitor of metalloproteinases-like, OB-fold.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression.
Peak expression observed at stages throughout embryogenesis, during early larval stages, at stages throughout the pupal period.
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