Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name caup
Flybase description The gene caupolican is referred to in FlyBase by the symbol Dmel\caup (CG10605, FBgn0015919).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -51.6901 1.4188 -46.190629 -49.3474 -66.144777 -53.4246 -57.52755 -13.720698
    Affimetrix absolute value 2.751 8.116 2.663 2.778 2.717 2.822 2.705 4.624
    Affymetric present call in "x" number of chips 0 3 0 0 0 0 0 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: sequence-specific enhancer binding RNA polymerase II transcription factor activity.
There is experimental evidence that it is involved in the biological process: imaginal disc-derived wing vein specification; compound eye morphogenesis; phagocytosis, engulfment.
14 alleles are reported.
The phenotypes of these alleles are annotated with: mesothoracic segment; eye; macrochaeta; notopleural suture; vertical bristle; wing; microchaeta; ommatidium; scutellum.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Homeobox; Homeobox KN domain; Homeobox, conserved site; Homeodomain-like; Homeodomain-related; Iroquois-class homeodomain protein.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 06-18 hour embryonic stages.
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