Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name vri
Flybase description The gene vrille is referred to in FlyBase by the symbol Dmel\vri (CG14029, FBgn0016076).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.0878 -0.5158 -1.754081 -2.5075 -2.347093 -1.6575 -0.90122 -1.867674
    Affimetrix absolute value 7.383 7.41 7.375 7.129 7.54 7.865 7.975 7.366
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: protein homodimerization activity; protein heterodimerization activity.
There is experimental evidence that it is involved in the biological process: cellular process; circadian rhythm; bristle morphogenesis; open tracheal system development; imaginal disc-derived wing hair organization.
35 alleles are reported.
The phenotypes of these alleles are annotated with 18 unique terms, many of which group under: organ system subdivision; adult segment; organ system; external compound sense organ; thoracic segment; integumentary plate; tracheal system; imaginal precursor; dorsal closure embryo; peripheral nervous system.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Basic leucine zipper; Basic-leucine zipper (bZIP) transcription factor.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression.
Peak expression observed within 12-18 embryonic stages, during late pupal stages.
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