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| Gene name | Cdk4 | ||||||||||||||||||||||||||||||||||||
| Flybase description | The gene Cyclin-dependent kinase 4 is referred to in FlyBase by the symbol Dmel\Cdk4 (CG5072, FBgn0016131). | ||||||||||||||||||||||||||||||||||||
| Expression data along the gut |
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| Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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| Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: cyclin binding. There is experimental evidence that it is involved in the biological process: blastoderm segmentation; cell proliferation; cell growth; JAK-STAT cascade; cell cycle; mitochondrion organization; open tracheal system development. 35 alleles are reported. The phenotypes of these alleles are annotated with: embryonic/first instar larval cuticle; adult; abdominal 4 ventral denticle belt; cell cycle; mesothoracic tergum; wing; embryo; denticle belt. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 06-12 hour embryonic stages. . |
