Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Past1
Flybase description The gene Putative Achaete Scute Target 1 is referred to in FlyBase by the symbol Dmel\Past1 (CG6148, FBgn0016693).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 1.6839 4.4673 3.411485 3.8922 1.945494 2.762 2.49052 2.887627
    Affimetrix absolute value 9.143 9.774 9.943 10.34 9.703 10.013 9.861 9.759
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: calcium ion binding.
There is experimental evidence that it is involved in the biological process: endocytosis; imaginal disc-derived wing margin morphogenesis; sperm individualization; imaginal disc-derived wing vein specification; oogenesis.
10 alleles are reported.
The phenotypes of these alleles are annotated with: ovary; oocyte; embryonic/larval garland cell; testis; cystic bulge; egg chamber; spermatid cyst; individualization stage spermatid.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Dynamin, GTPase domain; EF-HAND 2; EF-Hand 1, calcium-binding site; EF-hand-like domain; EPS15 homology (EH).
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression.
Peak expression observed within 06-12 and 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.
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