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Gene name | spen | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene split ends is referred to in FlyBase by the symbol Dmel\spen (CG18497, FBgn0016977). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: nucleotide binding; nucleic acid binding. There is experimental evidence for 12 unique biological process terms, many of which group under: biological regulation; system development; cellular component organization or biogenesis; post-embryonic organ morphogenesis; cell fate commitment; cellular process; appendage development; neuroblast fate commitment; localization; sensory organ development; segment specification. 96 alleles are reported. The phenotypes of these alleles are annotated with 29 unique terms, many of which group under: organ system; organ system subdivision; cephalopharyngeal skeleton; peripheral nervous system; external compound sense organ; pharyngeal sclerite; acellular anatomical structure; eo support cell; non-connected developing system; embryonic thorax. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Nucleotide-binding, alpha-beta plait; RNA recognition motif domain; Spen Paralogue and Orthologue SPOC, C-terminal-like; Spen paralogue and orthologue SPOC, C-terminal; Spen paralogue/orthologue C-terminal, metazoa. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the pupal period. . |