Flygut: an atlas of the Drosophila adult midgut

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Gene name sktl
Flybase description The gene skittles is referred to in FlyBase by the symbol Dmel\sktl (CG9985, FBgn0016984).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -4.1992 -1.8046 -2.885549 -3.0747 -6.061029 -3.6427 -2.96187 -4.077954
    Affimetrix absolute value 6.339 6.779 6.665 6.799 6.176 6.704 7.019 6.224
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: 1-phosphatidylinositol-4-phosphate 5-kinase activity.
There is experimental evidence that it is involved in the biological process: spermatid development; maintenance of oocyte nucleus location involved in oocyte dorsal/ventral axis specification; oocyte microtubule cytoskeleton polarization; autophagic cell death; cortical actin cytoskeleton organization; salivary gland cell autophagic cell death; peripheral nervous system development.
35 alleles are reported.
The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: multicellular structure; anatomical structure; cytoplasmic part; cell part; organ system; organ system subdivision; adult segment; acellular anatomical structure; egg; thoracic segment; sense organ; non-connected developing system; imaginal precursor.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Phosphatidylinositol-4-phosphate 5-kinase; Phosphatidylinositol-4-phosphate 5-kinase, core; Phosphatidylinositol-4-phosphate 5-kinase, core, subgroup.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages, in adult female stages.
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