Flygut: an atlas of the Drosophila adult midgut

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Gene name Pdk
Flybase description The gene Pyruvate dehydrogenase kinase is referred to in FlyBase by the symbol Dmel\Pdk (CG8808, FBgn0017558).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -0.3798 -0.238 -2.40103 -1.4468 -2.640798 3.7097 1.81244 -1.707892
    Affimetrix absolute value 8.347 7.733 6.98 7.864 7.423 10.414 9.384 7.603
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: pyruvate dehydrogenase (acetyl-transferring) kinase activity.
Based on sequence similarity, it is predicted to be involved in the biological process: pyruvate metabolic process.
13 alleles are reported.
No phenotypic data is available.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: ATPase-like, ATP-binding domain; Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal; Signal transduction histidine kinase, core.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 and 18-24 hour embryonic stages, during late larval stages, during late pupal stages.
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