Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Ork1
Flybase description The gene Open rectifier K+ channel 1 is referred to in FlyBase by the symbol Dmel\Ork1 (CG1615, FBgn0017561).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -46.5743 -12.5249 -2.632214 -1.4559 -52.853268 -49.8681 -1.91147 -6.900925
    Affimetrix absolute value 2.891 3.975 6.809 7.846 3.077 2.929 7.652 5.502
    Affymetric present call in "x" number of chips 0 3 3 3 0 0 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: outward rectifier potassium channel activity; potassium channel activity; inward rectifier potassium channel activity.
There is experimental evidence that it is involved in the biological process: locomotor rhythm; regulation of heart rate.
12 alleles are reported.
The phenotype of these alleles is annotated with: embryonic/larval heart.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Ion transport 2; Potassium channel, two pore.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 00-06 hour embryonic stages, in adult female stages.
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