Flygut: an atlas of the Drosophila adult midgut

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Gene name toy
Flybase description The gene twin of eyeless is referred to in FlyBase by the symbol Dmel\toy (CG11186, FBgn0019650).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -65.5305 -41.1651 -47.8221 -61.8485 -74.252894 -72.772 -73.36926 -61.26198
    Affimetrix absolute value 2.378 2.269 2.611 2.443 2.545 2.379 2.354 2.342
    Affymetric present call in "x" number of chips 0 1 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: sequence-specific DNA binding transcription factor activity.
There is experimental evidence that it is involved in the biological process: brain morphogenesis; positive regulation of gene expression; eye-antennal disc development; ocellus development; mushroom body development.
21 alleles are reported.
The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: organ system subdivision; organ system; multicellular structure; adult segment; anatomical structure; imaginal precursor; adult; embryonic/larval imaginal precursor; thoracic segment; region of integument; non-connected developing system.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Homeobox; Homeobox, conserved site; Homeodomain-like; Homeodomain-related; Paired box protein, N-terminal; Winged helix-turn-helix transcription repressor DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression.
Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, at stages throughout the pupal period.
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