Flygut: an atlas of the Drosophila adult midgut

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Gene name Cbl
Flybase description The gene Cbl is referred to in FlyBase by the symbol Dmel\Cbl (CG7037, FBgn0020224).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -1.6423 1.4565 1.295386 0.4318 -0.584128 0.4507 -1.31494 0.302526
    Affimetrix absolute value 7.708 8.157 8.508 8.508 8.467 8.715 8.164 8.218
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence for 11 unique biological process terms, many of which group under: biological regulation; sensory organ development; multicellular organism reproduction; dorsal/ventral axis specification; neuron differentiation; regulation of epidermal growth factor receptor signaling pathway; gamete generation; ovarian follicle cell development; localization; post-embryonic organ morphogenesis; system development; establishment or maintenance of polarity of follicular epithelium; axis specification.
31 alleles are reported.
The phenotypes of these alleles are annotated with 17 unique terms, many of which group under: organ system; organ system subdivision; adult segment; external compound sense organ; thoracic segment; adult; peripheral nervous system; cell part; cephalopharyngeal skeleton; cell periphery.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Adaptor protein Cbl; Adaptor protein Cbl, EF hand-like; Adaptor protein Cbl, N-terminal helical; Adaptor protein Cbl, PTB domain; Adaptor protein Cbl, SH2-like; EF-hand-like domain; SH2 motif; UBA-like; Ubiquitin-associated/translation elongation factor EF1B, N-terminal; Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote; Zinc finger, C3HC4 RING-type; Zinc finger, RING-type; Zinc finger, RING-type, conserved site; Zinc finger, RING/FYVE/PHD-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed within 00-06 hour embryonic stages.
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