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Gene name | Cbl | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Cbl is referred to in FlyBase by the symbol Dmel\Cbl (CG7037, FBgn0020224). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding. There is experimental evidence for 11 unique biological process terms, many of which group under: biological regulation; sensory organ development; multicellular organism reproduction; dorsal/ventral axis specification; neuron differentiation; regulation of epidermal growth factor receptor signaling pathway; gamete generation; ovarian follicle cell development; localization; post-embryonic organ morphogenesis; system development; establishment or maintenance of polarity of follicular epithelium; axis specification. 31 alleles are reported. The phenotypes of these alleles are annotated with 17 unique terms, many of which group under: organ system; organ system subdivision; adult segment; external compound sense organ; thoracic segment; adult; peripheral nervous system; cell part; cephalopharyngeal skeleton; cell periphery. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Adaptor protein Cbl; Adaptor protein Cbl, EF hand-like; Adaptor protein Cbl, N-terminal helical; Adaptor protein Cbl, PTB domain; Adaptor protein Cbl, SH2-like; EF-hand-like domain; SH2 motif; UBA-like; Ubiquitin-associated/translation elongation factor EF1B, N-terminal; Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote; Zinc finger, C3HC4 RING-type; Zinc finger, RING-type; Zinc finger, RING-type, conserved site; Zinc finger, RING/FYVE/PHD-type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages. . |