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Gene name | ATPCL | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene ATP citrate lyase is referred to in FlyBase by the symbol Dmel\ATPCL (CG8322, FBgn0020236). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: ATP citrate synthase activity. Based on sequence similarity, it is predicted to be involved in the biological process: citrate metabolic process; acetyl-CoA biosynthetic process. 14 alleles are reported. The phenotype of these alleles is annotated with: mesothoracic tergum. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: ATP-citrate lyase/succinyl-CoA ligase; ATP-citrate lyase/succinyl-CoA ligase, active site; ATP-citrate synthase; ATP-grasp fold, subdomain 2; ATP-grasp fold, succinyl-CoA synthetase-type; Citrate synthase-like; Citrate synthase-like, core; Citrate synthase-like, large alpha subdomain; Citrate synthase-like, small alpha subdomain; CoA-binding; NAD(P)-binding domain; Succinyl-CoA ligase, alpha subunit; Succinyl-CoA synthetase, beta subunit, conserved site; Succinyl-CoA synthetase-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed within 00-18 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes. . |