Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name stet
Flybase description The gene stem cell tumor is referred to in FlyBase by the symbol Dmel\stet (CG33166, FBgn0020248).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -54.0752 -38.4561 -62.48791 -68.9563 -86.391587 -76.9032 -82.44906 -69.970701
    Affimetrix absolute value 2.665 2.367 2.219 2.284 2.331 2.314 2.191 2.167
    Affymetric present call in "x" number of chips 1 2 0 0 0 1 0 1
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: serine-type peptidase activity.
It is reported to be involved in the biological process: epidermal growth factor receptor signaling pathway.
35 alleles are reported.
The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: organ system; multicellular structure; anatomical structure; portion of tissue; ovariole; cell part; acellular anatomical structure; adult segment; cell periphery; organ system subdivision; gonadal sheath.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: EF-HAND 2; EF-hand-like domain; Peptidase S54, rhomboid; Peptidase S54, rhomboid domain; Peptidase S54, rhomboid, metazoan.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.
Peak expression observed within 00-06 hour embryonic stages, in adult female stages.
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