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Gene name | sfl | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene sulfateless is referred to in FlyBase by the symbol Dmel\sfl (CG8339, FBgn0020251). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: [heparan sulfate]-glucosamine N-sulfotransferase activity. There is experimental evidence that it is involved in the biological process: fibroblast growth factor receptor signaling pathway; glycosaminoglycan biosynthetic process; mesoderm migration involved in gastrulation; synaptic vesicle endocytosis; intracellular distribution of mitochondria; heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; sulfur compound metabolic process; Wnt receptor signaling pathway; segment polarity determination; epithelial cell migration, open tracheal system. 17 alleles are reported. The phenotypes of these alleles are annotated with 14 unique terms, many of which group under: organ system; multicellular structure; portion of tissue; tracheal system; anatomical structure; acellular anatomical structure; organ system subdivision; non-connected developing system; synapse; embryonic/larval integumentary system; adult segment. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Heparan sulphate-N-deacetylase; Sulfotransferase domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-18 hour embryonic stages. . |