Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name ko
Flybase description The gene knockout is referred to in FlyBase by the symbol Dmel\ko (CG10573, FBgn0020294).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -12.7684 -2.4148 -28.199243 -20.3242 -50.797181 -35.8704 -18.19824 -28.352342
    Affimetrix absolute value 4.782 6.383 3.391 4.066 3.096 3.399 4.379 3.528
    Affymetric present call in "x" number of chips 3 3 2 3 0 2 3 2
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Its molecular function is unknown.
There is experimental evidence that it is involved in the biological process: motor axon guidance.
15 alleles are reported.
The phenotypes of these alleles are annotated with: RP5 neuron; RP3 neuron.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Storkhead-box protein, winged-helix domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 12-18 embryonic stages, during late larval stages, at stages throughout the pupal period.
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