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Gene name | Dredd | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Death related ced-3/Nedd2-like protein is referred to in FlyBase by the symbol Dmel\Dredd (CG7486, FBgn0020381). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding; apoptotic protease activator activity; endopeptidase activity. There is experimental evidence that it is involved in the biological process: immune response; apoptosis; peripheral nervous system neuron development; sperm individualization; defense response to Gram-negative bacterium; peptidoglycan recognition protein signaling pathway; defense response; protein maturation by peptide bond cleavage. 31 alleles are reported. The phenotypes of these alleles are annotated with: spermatid; mesothoracic tergum. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Peptidase C14, ICE, catalytic subunit p20; Peptidase C14, caspase catalytic; Peptidase C14, caspase non-catalytic subunit p10; Peptidase C14, caspase precursor p45; Peptidase C14, caspase precursor p45, core. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed during late larval stages, at stages throughout the pupal period. . |