Home | Overview of gut regions | Anatomy | Histology | Transgene expression mapping | Gene expression |
Search expression data by gene: |
Gene name | pug | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene pugilist is referred to in FlyBase by the symbol Dmel\pug (CG4067, FBgn0020385). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
|
||||||||||||||||||||||||||||||||||||
Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
||||||||||||||||||||||||||||||||||||
Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: methylenetetrahydrofolate dehydrogenase (NADP+) activity; formate-tetrahydrofolate ligase activity; methenyltetrahydrofolate cyclohydrolase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: oxidation-reduction process; folic acid-containing compound biosynthetic process. 18 alleles are reported. The phenotypes of these alleles are annotated with: eye; pigment cell. It has 5 annotated transcripts and 5 annotated polypeptides. Protein features are: Formate-tetrahydrofolate ligase, FTHFS; Formate-tetrahydrofolate ligase, FTHFS, conserved site; NAD(P)-binding domain; Tetrahydrofolate dehydrogenase/cyclohydrolase; Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed during early larval stages, during early pupal stages. . |