Flygut: an atlas of the Drosophila adult midgut

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Gene name Fak56D
Flybase description The gene Focal Adhesion Kinase is referred to in FlyBase by the symbol Dmel\Fak56D (CG10023, FBgn0020440).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -12.9079 -5.4647 -9.118277 -6.5447 -13.171244 -7.185 -9.93119 -11.59254
    Affimetrix absolute value 4.799 5.179 5.035 5.685 5.094 5.717 5.292 4.779
    Affymetric present call in "x" number of chips 2 3 3 3 2 3 3 2
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: protein tyrosine kinase activity; non-membrane spanning protein tyrosine kinase activity.
There is experimental evidence that it is involved in the biological process: regulation of cell shape.
14 alleles are reported.
The phenotypes of these alleles are annotated with: embryonic/larval optic stalk; bouton; synapse; subretinal glial cell.
It has 6 annotated transcripts and 6 annotated polypeptides.
Protein features are: Band 4.
1 domain; FERM central domain; FERM domain; Focal adhesion kinase, targeting (FAT) domain; Protein kinase, catalytic domain; Protein kinase-like domain; Serine-threonine/tyrosine-protein kinase; Tyrosine-protein kinase, active site; Tyrosine-protein kinase, catalytic domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 12-18 embryonic stages.
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