Flygut: an atlas of the Drosophila adult midgut

 Mouche Logo lab lemaitre Bbcf logo
Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name Dad
Flybase description The gene Daughters against dpp is referred to in FlyBase by the symbol Dmel\Dad (CG5201, FBgn0020493).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -0.3507 -0.5182 -2.119511 0.3122 -4.290531 -2.113 -0.70033 -2.746207
    Affimetrix absolute value 8.381 7.397 7.122 8.365 6.711 7.489 8.175 6.896
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity.
There is experimental evidence for 12 unique biological process terms, many of which group under: post-embryonic organ morphogenesis; biological regulation; system development; cellular component organization or biogenesis; regulation of developmental process; instar larval or pupal morphogenesis; localization; instar larval development; digestive tract development; renal tubule development; cellular component movement; regionalization; negative regulation of transforming growth factor beta receptor signaling pathway; growth; neuron differentiation.
33 alleles are reported.
The phenotypes of these alleles are annotated with 34 unique terms, many of which group under: organ system; organ system subdivision; adult segment; thoracic segment; portion of tissue; imaginal precursor; late extended germ band embryo; peripheral nervous system; dorsal branch primordium; organelle; synapse; external compound sense organ.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Dwarfin; MAD homology 1, Dwarfin-type; MAD homology, MH1; SMAD domain, Dwarfin-type; SMAD domain-like; SMAD/FHA domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 06-12 hour embryonic stages, during early pupal stages.
.