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Gene name | CtBP | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene C-terminal Binding Protein is referred to in FlyBase by the symbol Dmel\CtBP (CG7583, FBgn0020496). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding; transcription factor binding; protein homodimerization activity; transcription corepressor activity; transcription coactivator activity. There is experimental evidence that it is involved in the biological process: bristle development; wing disc development; regulation of Wnt receptor signaling pathway; regulation of transcription, DNA-dependent; embryonic development via the syncytial blastoderm; regulation of transcription from RNA polymerase II promoter; Wnt receptor signaling pathway. 64 alleles are reported. The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: adult segment; organ system subdivision; organ system; thoracic segment; adult; integumentary plate; sense organ; multicellular structure; embryonic/larval hemocoel; eo support cell. It has 5 annotated transcripts and 5 annotated polypeptides. Protein features are: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; NAD(P)-binding domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-12 hour embryonic stages. . |