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Gene name | Pkn | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Protein kinase related to protein kinase N is referred to in FlyBase by the symbol Dmel\Pkn (CG2049, FBgn0020621). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein kinase activity. There is experimental evidence that it is involved in the biological process: dorsal closure. 48 alleles are reported. The phenotypes of these alleles are annotated with: dorsal closure embryo; anterior wing margin; wing margin bristle; posterior wing margin; wing; ommatidium; wing hair. It has 12 annotated transcripts and 12 annotated polypeptides. Protein features are: AGC-kinase, C-terminal; C2 calcium-dependent membrane targeting; C2 calcium/lipid-binding domain, CaLB; HR1 repeat, rho-binding; HR1 rho-binding repeat; Protein kinase, ATP binding site; Protein kinase, C-terminal; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in adult female stages. . |