Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Pi3K21B
Flybase description The gene Pi3K21B is referred to in FlyBase by the symbol Dmel\Pi3K21B (CG2699, FBgn0020622).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -3.1104 1.4676 1.438729 -1.3891 -1.586404 -0.3308 -2.01266 -1.331196
    Affimetrix absolute value 6.779 8.171 8.68 7.943 8.124 8.554 7.554 7.835
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: kinase binding.
There is experimental evidence that it is involved in the biological process: phosphatidylinositol phosphorylation; protein phosphorylation; regulation of cell proliferation; regulation of cell size; lipid phosphorylation.
12 alleles are reported.
The phenotypes of these alleles are annotated with: embryonic/larval salivary gland; mushroom body neuroblast; embryonic/larval ganglionic branch.
It has one annotated transcript and one annotated polypeptide.
Protein features are: PI3 kinase, P85 regulatory subunit; SH2 motif.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-06 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages.
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